The lab is affiliated with the Department of Molecular Medicine, School of Medicine, Sapienza University of Rome, Rome. Lab facilities are located at the DEM Sapienza and at the Biomedical Science Park of Rome.

The focus of the lab is on postnatal stem cells in the human bone marrow and in other mesoderm-derived tissues. Postnatal stem cells are viewed as a crucial system for modeling and treating diseases of bone and other tissues that do not have a cure. Work conducted in the lab aims at i) the biological definition of identity, properties, phenotype and ontogeny of postnatal stem cells, ii) their use for modeling diseases of bone and other tissues in order to define key pathogenetic mechansisms, iii) their use  for developing  therapeutic strategies. 

Fibrous Dysplasia (McCune-Albright Syndrome, OMIM#174800) is our current major target.